Transcript_15

cmscan-Rfam

Family :

mir-17

Id:

RF00051

Type:

Gene; miRNA;

Taxonomy:

Eukaryota;

Ontology:

GO:0035195 gene silencing by miRNARF00051

Description:

This family represents the microRNA (miRNA) precursor mir-17, family, which includes mir-20, mir-91, and mir-103. miRNAs
are transcribed as ~70nt precursors (modelled here) and subsequently processed by the Dicer enzyme to
give a ~22nt product. In this case the mature sequence comes from the 3' arm
of the precursor. The extents of the hairpin precursors are not generally known and are
estimated based on hairpin prediction. The products are thought to have regulatory roles through complementarity
to mRNA. The involvement of Dicer in miRNA processing suggests a relationship with the phenomenon
of RNA interference. miRNAs are numbered based on the sequence of the mature RNA.

Score:

75.6

E-value:

3.9e-19

From sequence:

389

To sequence:

471

Alignments:

                                        v                                        v                      NC
                    :::::<<<<<<<--<<<<<<<<-<<-<<<<<-<<<.____________>>>>>>>>->>->>>>>>>>--->>>>>>>::::: CS
        RF00051   1 cCuuaguaGuGcuAAAGUGCucAcAGUGCaGGUAG.ugUUuuguucAUCUACuGCAuUguggGCACUUguagCaCuacuaugg 82 
                    +CU +G:A:U C+AAAGUGC CACAGUGCAGGUAG UG U ++U  AUCUACUGCA+UGUG GCACUUGUAG A:U:CU++G 
  Transcript_15 389 UCUGGGCAAUUCCAAAGUGCUCACAGUGCAGGUAGcUGCUCACUGGAUCUACUGCAGUGUGUGCACUUGUAGGAUUGCUGGGC 471
                    ***********************************999********************************************* PP

RNAfold

>Transcript_15
CUGGGCAAUUCCAAAGUGCUCACAGUGCAGGUAGCUGCUCACUGGAUCUA
CUGCAGUGUGUGCACUUGUAGGAUUGCUGGGC
((.((((((((..((((((.((((.(((((.(((.(.(.....).).)))))))).)))).))))))...)))))))).)). (-39.00)

Length sequence

: 82

Length match:

81